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spoIIAB [2017-05-10 17:29:54]
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spoIIAB [2017-05-10 17:29:54]

anti-protein serine kinase
Locus
BSU23460
Isoelectric point
4.38
Molecular weight
16.21 kDa
Protein length
146 aa Sequence Blast
Gene length
438 bp Sequence Blast
Function
control of SigF activity septation; phosphorylation and inactivation of SpoIIAA
Product
anti-protein serine kinase
Essential
no
Synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Information processing → Protein synthesis, modification and degradation → Protein modification → Protein kinases
  • Information processing → Regulation of gene expression → Sigma factors and their control → Control of sigma factors
  • Lifestyles → Sporulation → Sporulation proteins → Sporulation proteins/ other

    • Gene

    Coordinates
    2,444,208 → 2,444,648

    The protein

    Catalyzed reaction/ biological activity

  • ATP + a protein = ADP + a phosphoprotein (according to Swiss-Prot)

    • Protein family

  • anti-sigma-factor family (according to Swiss-Prot)

    • Structure

  • 1L0O (complex with SigF, Geobacillus stearothermophilus) PubMed
  • 1TIL (complex with SpoIIAA, Geobacillus stearothermophilus)

    • Expression and Regulation

    Operons

    Genes
    spoIIAA-spoIIAB-sigF
    Description
    PubMed

    Sigma factors

  • SigF: sigma factor, in SigF regulon
  • SigG: sigma factor, in SigG regulon
  • SigH: sigma factor, in SigH regulon

    • Regulatory mechanism

  • Spo0A: activation, PubMed, in Spo0A regulon
  • AbrB: repression, PubMed, in AbrB regulon
  • SinR: repression, in SinR regulon

    • Regulation

  • spoIIAA: expressed early during sporulation
    • view in new tab

    Genes
    dacF-spoIIAA-spoIIAB-sigF
    Description
    PubMed

    Sigma factors

  • SigF: sigma factor, PubMed, in SigF regulon
  • SigG: sigma factor, in SigG regulon

    • Regulatory mechanism

  • AbrB: repression, PubMed, in AbrB regulon

    • Regulation

  • spoIIAA: expressed early during sporulation
  • strongly repressed in the presence of salt (1.2 M NaCl) PubMed
    • view in new tab

    Labs working on this gene/protein

  • Charles Moran, Emory University, NC, USA homepage

    • References

    Modeling of SigF activation

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    Original Publications

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